fbpx

Mechanisms Underlying Effectiveness of PI3Kd-Inhibited T Cells for Adoptive Cell Transfer Therapy

Guillermo Omar Rangel Rivera

Mentor Chrystal M. Paulos, PhD
Award Type Medical Student Award
Institution Medical University of South Carolina
Donor Support In honor of Christopher Westdyk
Description:

Findings from this grant will shed light on 1) how stemness is sustained by modulating PI3Kδ signaling in T cells using FDA-approved drugs and 2) how transcription regulation in T cell mitochondria contributes to tumor immunity.