While immunotherapy has revolutionized the management of advanced melanoma, many patients still do not benefit from this treatment strategy. Indeed, currently available imm...

Cancer treatment was revolutionized when scientists discovered how to activate a patients’ own immune system to fight tumors. Unfortunately, some patients have tumors tha...

Over the past decade, harnessing the power of a patient’s own immune system for the treatment of cancer has been a major medical breakthrough. By using drugs to block inh...

The majority of cancer patients do not yet benefit from immunotherapy, including from immune checkpoint therapies that invigorate the patients’ own immune systems to figh...

Melanoma is one of the fastest growing malignancies and accounts for 5.5% of all new cancer cases in the United States. Treatment options and prognosis of melanoma patients...

Successful management of melanoma will require eliminating both the primary cancer as well as its spread. The survival of melanoma patients reduces significantly ...

The development of new classes of drugs which target pathways required for melanoma growth and approaches to increase tumor immunogenicity (Immune Checkpoint Blockade (ICB)...

Melanoma is the most serious type of skin cancer that can spread to other parts of the body, where it becomes difficult to treat and can be fatal. Over half of all melanoma...

Protective mechanisms called “immune evasion” thus making it difficult for immunotherapies to be fully effective and to lead to complete cure. These mechanisms have onl...