Successful management of melanoma will require eliminating both the primary cancer as well as its spread. The survival of melanoma patients reduces significantly ...

The development of new classes of drugs which target pathways required for melanoma growth and approaches to increase tumor immunogenicity (Immune Checkpoint Blockade (ICB)...

Melanoma is the most serious type of skin cancer that can spread to other parts of the body, where it becomes difficult to treat and can be fatal. Over half of all melanoma...

Protective mechanisms called “immune evasion” thus making it difficult for immunotherapies to be fully effective and to lead to complete cure. These mechanisms have onl...

Melanoma is the deadliest form of skin cancer, and despite the exciting advancements in treatment, there is still no cure for late stage disease. The incidence of...

Melanoma immunotherapy works by stimulating immune cells to kill tumor. In many cases, immune cells are drawn to tumor by immunogenic proteins on the surface...

Melanoma, one of the most aggressive and fatal neoplasms, is responsible for over 80% of skin cancer-related deaths. As melanoma mostly expresses tumor-specific neo-antigen...

Study Goals: Reveal how a molecule called neuritin supports a population of immune cells that actively interferes with the killing of melanomas; determine if ther...

Description: Melanoma of the uveal tract (a region of the eye) is the most common ocular malignancy in adults and accounts for 5% of all melanomas. According to N...

Description: Mutations in a small number of genes are found in a large fraction of human melanomas. For instance, so-called “driver” mutations in the “famous” melan...