Melanoma is the most lethal skin cancer and when detected at an advanced stage in which cells have spread throughout the body (known as metastasis), success of currently av...

Over the past decade, harnessing the power of a patient’s own immune system for the treatment of cancer has been a major medical breakthrough. By using drugs to block inh...

The majority of cancer patients do not yet benefit from immunotherapy, including from immune checkpoint therapies that invigorate the patients’ own immune systems to figh...

Melanoma is one of the fastest growing malignancies and accounts for 5.5% of all new cancer cases in the United States. Treatment options and prognosis of melanoma patients...

Successful management of melanoma will require eliminating both the primary cancer as well as its spread. The survival of melanoma patients reduces significantly ...

The development of new classes of drugs which target pathways required for melanoma growth and approaches to increase tumor immunogenicity (Immune Checkpoint Blockade (ICB)...

Melanoma is the most serious type of skin cancer that can spread to other parts of the body, where it becomes difficult to treat and can be fatal. Over half of all melanoma...

Protective mechanisms called “immune evasion” thus making it difficult for immunotherapies to be fully effective and to lead to complete cure. These mechanisms have onl...

Melanoma is the deadliest form of skin cancer, and despite the exciting advancements in treatment, there is still no cure for late stage disease. The incidence of...

Melanoma immunotherapy works by stimulating immune cells to kill tumor. In many cases, immune cells are drawn to tumor by immunogenic proteins on the surface...