James Mulé’s Abstract The proposed research will develop an innovative and clinically relevant class of nanomaterials—DNA-based “dendritic” (branched) nanostr...

Emily Bernstein‘s Abstract Melanoma is the most lethal skin cancer, and the success of current therapies remains limited. To better tailor melanoma treatments, we m...

Thorsten Mempel‘s Abstract While immunotherapy has greatly improved the survival for patients with melanoma of the sun-exposed skin, especially for those with adva...

Craig Ceol‘s Abstract The use of immunotherapies has revolutionized treatment for late-stage melanoma patients. These therapies have extended survival for many patien...

Kazuko Nishikura’s Abstract The phenomenon of “RNA editing” is a relatively recent discovery with exciting implications. RNA editing is a process that modifies th...

Current immunotherapies have dramatically improved clinical outcomes, but more than half of metastatic melanoma patients have poor responses and primary resistance. With ti...

Brain metastases remain a leading cause of death in patients with metastatic melanoma. One of the most exciting advances in the treatment of CNS metastases was combined che...

Immunotherapy has been remarkably successful in the treatment of melanoma, but not all patients benefit from therapy and its effects is in most cases temporary, followed by...

Our immune system operates on a balance of cells that that can destroy infected or cancerous tissue with those that prevent attacking healthy tissue. This equilibrium is af...