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FEATURED | January 24, 2025

The Melanoma Research Foundation Announces Rebrand...

Washington, DC (January 27, 2025) – The Melanoma Research Foundation (MRF), the largest independent organization devoted to melanoma, is excited to announce the official ...

3 Minute Read
December 19, 2023

Evaluation of cutaneous immune related adverse eve...

The treatment of melanoma with checkpoint inhibitor (CPI) therapy has produced rapid and substantial gains in survival, and as a result, the indications for its use have st...

3 Minute Read
December 19, 2023

Identification of molecular pathways that drive uv...

Uveal melanoma (UM) is a type of aggressive eye cancer that often spreads to the liver and has a poor prognosis. We don’t fully understand how UM spreads, which makes it ...

2 Minute Read
December 23, 2022

Exhausted CD8 T cells as an early indicator of lym...

Description: Immunotherapy has been shown to be effective in treating melanoma, even at an early stage of disease. Patients with Stage II melanoma are now able to receive a...

1 Minute Read
December 20, 2021

Control of Anti-Tumor Response by the Modulation o...

Traditional cancer therapy involves surgery, radiotherapy, and chemotherapy. These modalities aim to ablate the tumor, yet generally the disease relapses due to the ineffic...

2 Minute Read
December 20, 2020

Integrative Analysis of Prognostic Factors to Neoa...

Patients with lymph-node positive melanoma have a high risk of recurrence despite curative surgery. While adjuvant therapy given after surgery improves RFS and OS, ~25% of ...

1 Minute Read
December 20, 2019

The Development and Characterization of Cellular M...

Melanoma is the most aggressive form of skin cancer. Although progress has been made for advanced melanoma patients with 13 new FDA-approved therapies since 2011, resistanc...

3 Minute Read
December 20, 2019

Characterizing the Role of the Hippo Pathway Durin...

The Hippo pathway in cancer, mediated by YAP1, has been implicated in therapy resistance and aggressive tumor behavior in melanomas treated with targeted therapies. However...

1 Minute Read
December 20, 2017

Comprehensive Profiling of Immune Checkpoint Inhib...

Immune therapies termed “immune checkpoint inhibitors” remove key “brakes” on immune cells. These treatments lead to long-term responses and cures in some patients ...

2 Minute Read
January 6, 2016

Use of selective HDACi to improve antibody blockad...

Description: Immunotherapies, such as CTLA-4 or PD-1 inhibitors, have revolutionized the treatment of metastatic melanoma patients. However, a key challenge to optimize the...

2 Minute Read
January 6, 2015

Mechanisms controlling melanoma dormancy and metas...

0 Minute Read
January 6, 2015

MEK1/2-CDK4/6 targeting and acquired resistance me...

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January 6, 2014

Identifying rational therapeutic approaches to ...

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Apr 26, 2025 - Apr 27, 2025

Eyes on a Cure: Ocular Melanoma Patient & Caregiver Symposium

May 03, 2025

Miles for Melanoma Washington, DC

May 03, 2025

Mela-No-More Golf Tournament

May 10, 2025

Miles for Melanoma New England, MA

May 10, 2025

Stay Out of the Sun Run

May 10, 2025

The Ohio State University Patient and Caregiver Symposium

May 17, 2025

Melanoma Clinic Walk

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