Therapeutic Combinations against Melanoma Brain Metastases
Sixue Liu, PhD
Roger Lo, MD, PhD
Career Development Award
University of California, Los Angeles
Melanoma is a lethal form of skin cancer because it has a high propensity to metastasize, especially to the brain (often causing death). Compounding this problem is the observation that melanoma brain metastasis is relatively therapy resistant. We proposed a novel sequential-combinatorial therapy aimed at suppressing melanoma brain metastasis and designed studies (using novel molecular technologies) to understand the underlying mechanisms in order to accelerate clinical translation of our findings.
Career Development Award – Sixue Liu, PhD