Skip to content

Mechanisms Underlying Effectiveness of PI3Kd-Inhibited T Cells for Adoptive Cell Transfer Therapy

Guillermo Omar Rangel Rivera

Chrystal M. Paulos, PhD

Medical Student Award

Medical University of South Carolina

In honor of Christopher Westdyk

Description:

Findings from this grant will shed light on 1) how stemness is sustained by modulating PI3Kδ signaling in T cells using FDA-approved drugs and 2) how transcription regulation in T cell mitochondria contributes to tumor immunity.