I am 47 years old; mother of 3; my youngest being almost 8 years old. Just looking for advice from anyone who is undergoing targeted therapy ( Zelboraf & Cotellic). I am Stage 4....in January my yearly scan showed 2 masses in my leg where the cancer originated in 2006. Between January and now, shortly after starting immunotherapy, which I had to stop after 2 infusions because of elevated liver studies, the cancer spread to my right kidney. A month after spreading to my kidney, it spread to my stomach. I finally was given the go ahead to start the targeted therapy....had to wait for liver studies to be normal again.....which seemed like it took an eternity! Now I'm scared to death that that I'm going to eventually have to stop this treatment if my liver studies become elevated again. Any suggestions on how to get your liver to cooperate with the meds? I'm trying to eat as healthy as possible but if anyone else is going through the same treatment, I would love to hear from you. Even if it's to compare side effects. Right now I'm going into my second week and nausea and some vomitting have been my main side effects; along with extreme fatigue. This morning, however I woke up with the raised, red rash that's super itchy under both armpits and on my kneecaps. Everything I've read so far is the oatmeal baths help the best. Anxious to hear from someone....I feel very alone in all of this...even though I'm constantly surrounded by family members who want to help. I just know I would feel so much better to connect with others who are going through what I'm going through. Hope to hear from someone soon!