It has been 4 years since PET scans found 7 tumors in my lungs, Started the ipi/nivo combo and was NED at 1 year but continued on maintenance for 14 months and decided to stop as new evidence was showing maybe no improvement. This month is 3 years NED which is great but still fighting multiple side effects with fatigue being a never ending thing. My oncologist prescribe me Ritalin today as some research has shown this helps some patients with severe fatigue. Will see in the next couple of weeks. Good luck to everyone dealing with this nasty monster.