Find Support

Question re interpreting a pathology report

The information on this site is not intended or implied to be a substitute for professional medical advice, diagnosis or treatment. Content within the patient forum is user-generated and has not been reviewed by medical professionals. Other sections of the Melanoma Research Foundation website include information that has been reviewed by medical professionals as appropriate. All medical decisions should be made in consultation with your doctor or other qualified medical professional.

Question re interpreting a pathology report

Posted By
7/30/2010 7:00pm
View other posts by
Replies: 3

Just got my husbands pathology report from his LND today, and I am curious what this means:  "No areas of unequivocal capsular invation were demonstrated."  That sounds like a good thing.  Anyone know what "capsular invasion" is or if that tells us anything important?

Sorry if this is a dumb question or if I'm over-analyzing things.  I just want to understand everything about it that I can.

5 of 28 nodes were positive.  Amelanotic (same as primary 2 years ago) Currently Stage IIIC.  He's on the road to recovery and looking forward to life as an NED-er again!



It means that the melanoma is confined to the lymph node alone.  There was no sign that the melanoma was extending out of the lymph node capsule to the surrounding tissue.  That is a good thing.  The problem with melanoma is that even when it has not spread beyond the surface of the lymph node, it can spread through the lymphatic channels (which drains nodes) or through the blood system.  That is the fear we all have with Melanoma.  I hope that helps. I'll extend good wishes and prayers that your Dad continues to do well.


Sorry, that I said your Dad.  Yes I see it is your husband.  Sincere apologies.



Yes, it is a good thing. It means as far as they are aware, it did not go outside the nodes into surrounding tissue.




This information is for general patient educational & information purposes only. It should not be used for diagnosing/treating a health problem or disease. If you have or suspect you may have a health problem, you should consult your healthcare provider.