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IPI/NIVO Headaches, Fever, weakness

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IPI/NIVO Headaches, Fever, weakness

Posted By
THMoore
10/7/2020 6:59pm
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Replies: 8

Finished my second infusion 8 days ago. Now I’m having severe headaches and other symptoms. Told MDA and they gave me the list of side affects. They explained that if my headaches get worse, they want to scan earlier. My question is, I am taking Advil and the headaches go away fairly quick, but come back not as bad. If there are tumors or lesions in my brain, are the headaches constant of do they come and go ? I do know that headaches are part of the symptoms list, just asking what all of you that have gone through this know

Thanks Trent

Hi Trent, first point would be follow your dr. advice and the second point would be headaches with immunotherapy can be an indicator of endocrine issues like the pituitary being inflamed. Blood work and a brain scan can sort things out. Best Wishes!!!Ed

They said my thyroid was failing after the first infusion

Trent I had hypophysitis symptoms after first infusion of IPI. Within a week my pituitary was so swollen it was causing all kinds of issues. The headache was like a migraine except constant with no relief. Advil, Ibuprofen, etc....nothing worked. The headache was a throbbing whole head aching. Change of position from standing to lying and it got worse. Don't know if this helps, but if your symptoms are similar, get it checked out. Can cause aneurism if left to long.

Thx
Yea they did say my thyroid was not working properly. I go back in 2 weeks for blood work and will go from there. My headaches come and go. I take Advil and it’s works well. I am very weak and run a light fever on and off. Other then that, I am OK.

Thx
Yea they did say my thyroid was not working properly. I go back in 2 weeks for blood work and will go from there. My headaches come and go. I take Advil and it’s works well. I am very weak and run a light fever on and off. Other then that, I am OK.

Thx
Yea they did say my thyroid was not working properly. I go back in 2 weeks for blood work and will go from there. My headaches come and go. I take Advil and it’s works well. I am very weak and run a light fever on and off. Other then that, I am OK.

I had a brain tumor the size of a lemon in my brain and didn’t have a single headache. I asked my neurosurgeon about this after the procedure and he said headaches are not necessarily a primary symptom of brain tumors. So, I’d say your issue is more likely from treatment or one of the side effects others have pointed out.

Amanda

Stage IV — one brain met (resected via craniotomy 3/1/18 and subsequently treated with SRS) and two lung mets. Started Opdivo 4/16/18. Opdivo not eliminating lung mets, so on 12/5/18 started Ipi/Nivo combo.

Thank you Amanda. My headaches just come and go. Seems to help when I drink water. It might hurt in the front, then the back and then the sides. I’ve had 2 infusions with thyroid issues now. I hope your doing well

Hugs
Trent