I hope all of you warriors are fighting the good fight! I know I am..
I started ipi after my progression to stage 4. I had been on Nivo since last June and almost made it to the 1 year mark. After my second dose of Ipi, I noticed these transient fevers (the wife says I’m going through menopause). They were short lived and never went higher than 100.2. I received my third dose of Ipi two weeks ago. The fevers seemed to go away for that two week period of time. Last Friday I felt one of those fevers coming on. This time it went to 102.6 and stayed there until I took some Tylenol (500mg). This brought it down to a manageable 100.. The Tylenol only lasted for a couple hours. These fevers start around lunchtime and continue throughout the day. Nights are fun because the fever sort of breaks around midnight. The sweats that come along with the decrease in temperature are a fun way to sleep (can you say soaked. Aside from fever, there is a fairly substantial amount of body aches That comes along with it also. I’m set to receive my 4th dose on Friday.
I did a search and found a couple of postings for fever related side effects for ipi. It did not go into the Tylenol / Motrin Question I was looking for. My oncologist wants me to do 325 Tylenol then 400 Motrin every 4 hours. I tried that combo yesterday and was stuck with a temp around 101.
I was thinking about going with a longer acting ibuprofen like Aleve. The yo-yo effect between the Tylenol and Motrin is pretty hard to regulate.
The posts I located from other warriors were from around 2017. I’m just wondering if there is anyone else going down this road while on ipi.
(All labs came back pretty normal. Liver labs actually went down along with T4 labs)..
Fighting melanoma since 2004..