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Posted By
3/14/2016 7:53pm
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Replies: 8

Hi all
I'm trying to educate myself and I get a lille confused with some of the abbreviations, is there a list around here anywhere?

Bubbles - (3/14/2016 - 8:44pm)

Hi Suzi,

The short answer to your question is: no. There is no list. You would be better off to ask what it is that you are confused about...but....I'll give it a go....

NED - no evidence of disease

NEAD - no evidence of active disease (a rather new acronym in melanoma world)

Mets - metastatic disease

SLN - sentinel lymph node (the node most proximal to the lesion)

WLE - wide local excision (the area of tissue to remove around  a lesion to provide standardized accepted clear margins)

CLND - complete lymph node dissection (removal of all nodes in local area)

SRS - stereotactic radio surgery (radiation beamed in to one area from a variety of vantage points so surrounding tissue has minimal damage)

WBR - whole brain radiation

Immunotherapy - treatment that stimulates the immune system to attack tumors (types below)

Ipi - ipilimumab/yervoy - anti-CTLA 4 immunotherapy

Anti-PD-1 - nivo = nivolumab/opdivo or pembro = pembrolizumab/keytruda

ifn - interferon

Targeted therapy - therapy aimed at  a specific variation in a tumor 

BRAF or NRAS or CKIT ....some labels for different variations in tumors

BRAF i - BRAF inhibitors - meds for folks with those mutations

MEK - another place to block tumor metabolism, now found to make BRAFi work better, last longer and with fewer side effects and so are most often prescribed with BRAF inhibitors.

PR - partial response

CR - complete response

SD - stable diseae

ORR - overall response rate

DFS - disease free survivial

PFS - progression free survivial

OS - overall survival

DLT - dose limiting toxicity

AE - adverse event

Ir AE - immune related adverse event

WTF - whiskey tango foxtrot - you gotta have a sense of humor!

(Folks.....if you like this...please refer folks back to this cause...idhts (I don't have the strength!) To type this again!

Hope this helps. Wishing you all my best. Celeste

Maria C - (3/14/2016 - 9:29pm)

Celeste - this is phenomenal, thank you so much for putting this together!! I encourage you to copy & paste this list on your blog for reference for all your readers....what a great cheat sheet!

Many thanks!


Maria - Stage IV, MM, brain mets, responder to ipi/nivo combo

Janner - (3/14/2016 - 9:38pm)

There used to be an abbreviation list on this site, but it's no longer here.  I have nudged the MRF to think about adding it again.

Suzi - (3/15/2016 - 7:03am)

Thank you so much Celeste!
That answers my questions

Janner - (3/15/2016 - 11:16am)

There used to be an abbreviation list on this site.  I brought this post to the attention of the MRF and they are going to incorporate your list (and maybe others) into their Glossary of Terms.  I'm hoping for a new link at the top of the BB as well. 


ed williams - (3/16/2016 - 5:13pm)

Celeste, I think you should make up a quiz on Melanoma knowledge!!!!! True/False and multichoice questions are always fun!!!! Janner could make up one for all the new stage one and two patients. Great list by the way Celeste!!! MRF could run the test and make some money while they are at it, maybe charge $2.00 to take the test and have the funds go to research. Well, people will probably think it is more spam and not play, maybe it is not such a good idea!!!! Keep on doing what you do ladies, it makes a big difference for so many!!!! Ed

_Paul_ - (3/26/2016 - 12:54pm)

Ha! I love it! Especially WTF. Cancer takes so much but it doesn't have to take our sense of humor.

To exist is beyond fantastic.

Bubbles - (3/27/2016 - 10:20am)

Hee hee! Hope the Easter bunny comes to your luau! Happy day! C